Connectivity with Iain Duncan

Meta-analysis of PRP Studies

  • Current Status and Advancements in Platelet-Rich Plasma Therapy – Published in Cureus in October 2023.
  • Xiong, Y., Gong, C., Peng, et al (2023). Efficacy and safety of platelet-rich plasma injections for the treatment of osteoarthritis: a systematic review and meta-analysis of randomized controlled trials. In Frontiers in Medicine (Vol. 10). Frontiers Media SA.
  • Barman, A., Mishra, A., Maiti, R., et al (2022). Can platelet-rich plasma injections provide better pain relief and functional outcomes in persons with common shoulder diseases: a meta-analysis of randomized controlled trials. Clinics in Shoulder and Elbow, 25(1), 73–89.

List of references to 2021

  1. Migliorini, F., Driessen, A., Quack, V., Sippel, N., Cooper, B., Yasser, ·, Mansy, E., Tingart, M., & Eschweiler, J. (2021). Comparison between intra-articular infiltrations of placebo, steroids, hyaluronic and PRP for knee osteoarthritis: a Bayesian network meta-analysis. 141, 1473–1490.
  2. D, Z., JK, P., WY, Y., YH, H., LF, Z., GH, L., & J, L. (2021). Intra-Articular Injections of Platelet-Rich Plasma, Adipose Mesenchymal Stem Cells, and Bone Marrow Mesenchymal Stem Cells Associated With Better Outcomes Than Hyaluronic Acid and Saline in Knee Osteoarthritis: A Systematic Review and Network Meta-analysis. Arthroscopy : The Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 37(7), 2298-2314.e10.
  3. Görmeli, G., Görmeli, C. A., Ataoglu, B., Çolak, C., Aslantürk, O., & Ertem, K. (2017). Multiple PRP injections are more effective than single injections and hyaluronic acid in knees with early osteoarthritis: a randomized, double-blind, placebo-controlled trial. Knee Surgery, Sports Traumatology, Arthroscopy, 25(3), 958–965.
  4. Di Martino A, Di Matteo B, Papio T, et al. Platelet-Rich Plasma Versus Hyaluronic Acid Injections for the Treatment of Knee Osteoarthritis: Results at 5 Years of a Double-Blind, Randomized Controlled Trial. Am J Sports Med. 2019;47(2):347-354. https//doi:10.1177/0363546518814532
  5. Muchedzi, T. A., & Roberts, S. B. (2017). A systematic review of the effects of platelet rich plasma on outcomes for patients with knee osteoarthritis and following total knee arthroplasty. Surgeon, 1–9.
  6. Tan J, Chen H, Zhao L, Huang W. Platelet Rich Plasma Versus Hyaluronic Acid in the Treatment of Knee Osteoarthritis: a Meta-Analysis of 26 randomized controlled trials [published online ahead of print, 2020 Jul 14]. Arthroscopy. 2020;S0749-8063(20)30604-6. doi:10.1016/j.arthro.2020.07.011
  7. Park, G. Y., Kwon, D. R., Cho, H. K., Park, J., & Park, J. H. (2017). Distribution of platelet-rich plasma after ultrasound-guided injection for chronic elbow tendinopathies. Journal of Sports Science and Medicine, 16(1), 1–5.
  8. Mishra AK; Skrepnik NV; Edwards SG; Jones GL; Sampson S; Vermillion DA; Ramsey ML; Karli DC; Rettig AC. (2014). Efficacy of platelet-rich plasma for chronic tennis elbow: a double-blind, prospective, multicenter, randomized controlled trial of 230 patients. Am J Sports Med, 42(2), 463–471.
  9. Lundquist, W., & Stanford, R. (2013). Targeting systemic inflammation in patients with obesity-related pain: One practice’s success with platelet-rich plasma therapy. The Journal of Family Practice. [pii]
  10. Mi, B., Liu, G., Zhou, W., Lv, H., Liu, Y., Wu, Q., & Liu, J. (2017). Platelet rich plasma versus steroid on lateral epicondylitis: meta-analysis of randomized clinical trials. The Physician and Sportsmedicine, 0(0), 00913847.2017.1297670.
  11. Gosens, T., Peerbooms, J. C., van Laar, W., & den Oudsten, B. L. (2011). Ongoing Positive Effect of Platelet-Rich Plasma Versus Corticosteroid Injection in Lateral Epicondylitis. The American Journal of Sports Medicine, 39(6), 1200–1208.
  12. Sampson, S., Gerhardt, M., & Mandelbaum, B. (2008). Platelet rich plasma injection grafts for musculoskeletal injuries: a review. Curr.Rev.Musculoskelet.Med., 1(1935-973X (Print)), 165–174.
  13. Abate M Di Gregorio P, Pantalone A, Scuccimarra T, Vanni D, Andreoli E, Salini V, S. C. (2013). Comparison between hyaluronic acid and platelet rich plasma in the treatment of hip and knee osteoarthritis: Preliminary results. In Journal of orthopaedics and traumatology (Vol. 14, Issue 1 SUPPL. 1, p. S17).
  14. Shiple, B. J. (2013). How effective are injection treatments for lateral epicondylitis? Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine, 23(6), 502–503.
  15. Mishra, A., & Pavelko, T. (2006). Treatment of chronic elbow tendinosis with buffered platelet-rich plasma. The American Journal of Sports Medicine, 34(11), 1774–1778.
  16. Zhang, J. Y., Fabricant, P. D., Ishmael, C. R., Wang, J. C., Petrigliano, F. A., & Jones, K. J. (2016). Utilization of Platelet-Rich Plasma for Musculoskeletal Injuries. Orthopaedic Journal of Sports Medicine, 4(12), 232596711667624.
  17. Gobbi, A., Karnatzikos, G., Mahajan, V., & Malchira, S. (2012). Platelet-Rich Plasma Treatment in Symptomatic Patients With Knee Osteoarthritis. Sports Health: A Multidisciplinary Approach, 4(2), 162–172.
  18. Yadav, R. (2015). Comparison of Local Injection of Platelet Rich Plasma and Corticosteroids in the Treatment of Lateral Epicondylitis of Humerus. JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2(6), 1412–1420.
  19. Zhang, J. Y., Fabricant, P. D., Ishmael, C. R., Wang, J. C., Petrigliano, F. A., & Jones, K. J. (2016). Utilization of Platelet-Rich Plasma for Musculoskeletal Injuries. Orthopaedic Journal of Sports Medicine, 4(12), 232596711667624.
    Brief, T. (2013). Health Policy Advisory Committee on Technology Technology Brief (Issue August).
  20. Ridley, E. (2015). US-guided injections help ward off rotator cuff degeneration. AuntMinnie.
  21. Amable, P. R., Carias, R. B. V., Teixeira, M. V. T., da Cruz Pacheco, I., Corrêa do Amaral, R. J. F., Granjeiro, J. M., & Borojevic, R. (2013). Platelet-rich plasma preparation for regenerative medicine: optimization and quantification of cytokines and growth factors. Stem Cell Research & Therapy, 4(3), 67.
  22. Peerbooms, J. C., Sluimer, J., Bruijn, D. J., & Gosens, T. (2010). Positive effect of an autologous platelet concentrate in lateral epicondylitis in a double-blind randomized controlled trial: Platelet-rich plasma versus corticosteriod injection with a 1-year follow-up. Am J Sports Med, 38(2), 255–262.
  23. Fader, R. R., Mitchell, J. J., Traub, S., Nichols, R., Roper, M., Dan, O. M., & McCarty, E. C. (2014). Platelet-rich plasma treatment improves outcomes for chronic proximal hamstring injuries in an athletic population. Muscles, Ligaments and Tendons Journal, 4(4), 461–466.
  24. Filardo, G., Kon, E., Roffi, A., Di Matteo, B., Merli, M. L., & Marcacci, M. (2015). Platelet-rich plasma: why intra-articular? A systematic review of preclinical studies and clinical evidence on PRP for joint degeneration. Knee Surgery, Sports Traumatology, Arthroscopy, 23(9), 2459–2474.
  25. Tuakli-Wosornu, Y. A., Terry, A., Boachie-Adjei, K., Harrison, J. R., Gribbin, C. K., LaSalle, E. E., Nguyen, J. T., Solomon, J. L., & Lutz, G. E. (2016). Lumbar Intradiskal Platelet-Rich Plasma (PRP) Injections: A Prospective, Double-Blind, Randomized Controlled Study. PM & R : The Journal of Injury, Function, and Rehabilitation, 8(1), 1–10; quiz 10.
  26. Kececi, Y., Ozsu, S., & Bilgir, O. (2014). A cost-effective method for obtaining standard platelet-rich plasma. Wounds : A Compendium of Clinical Research and Practice, 26(8), 232–238.
  27. Tsikopoulos, K., Vasiliadis, H. S., & Mavridis, D. (2016). Injection therapies for plantar fasciopathy (‘plantar fasciitis’): a systematic review and network meta-analysis of 22 randomised controlled trials. British Journal of Sports Medicine, 1–10.
  28. Gobbi, a., Karnatzikos, G., Mahajan, V., & Malchira, S. (2012). Platelet-Rich Plasma Treatment in Symptomatic Patients With Knee Osteoarthritis: Preliminary Results in a Group of Active Patients. Sports Health: A Multidisciplinary Approach, 4(2), 162–172.
  29. Kaux, J. F., Drion, P., Croisier, J. L., & Crielaard, J. M. (2015). Tendinopathies and platelet-rich plasma (PRP): From pre-clinical experiments to therapeutic use. Journal of Stem Cells and Regenerative Medicine, 11(1), P7–P17.
  30. Randelli, P., Randelli, F., Ragone, V., Menon, A., D’Ambrosi, R., Cucchi, D., Cabitza, P., & Banfi, G. (2014). Regenerative medicine in rotator cuff injuries. BioMed Research International, 2014.
  31. Schapiro, A., Health, P., Convention, A., Vista, L. B., & Prp, B. (2015). Imaging Detects Treatment Response in Epicondylosis. MEDSCAPE MEDICAL NEWS, 22–24.
  32. Miller LE, Parrish WR, Roides B, et al (2017). Efficacy of platelet-rich plasma injections for symptomatic tendinopathy: systematic review and meta-analysis of randomised injection-controlled trials BMJ Open Sport & Exercise Medicine 2017;3. Open Access.
  33. Napolitano, M., Matera, S., Bossio, M., Crescibene, A., Costabile, E., Almolla, J., Almolla, H., Togo, F., Giannuzzi, C., & Guido, G. (2012). Autologous platelet gel for tissue regeneration in degenerative disorders of the knee. Blood Transfusion, 10(1), 72–77.
  34. Jacob, G., Shetty, V., & Shetty, S. (2017). A study assessing intra-articular PRP vs PRP with HMW HA vs PRP with LMW HA in early knee osteoarthritis. Journal of Arthroscopy and Joint Surgery, 4(2), 65–71.
  35. Fitzpatrick J, Bulsara MK, O’Donnell J, McCrory PR, Zheng MH. The Effectiveness of Platelet-Rich Plasma Injections in Gluteal Tendinopathy: A Randomized, Double-Blind Controlled Trial Comparing a Single Platelet-Rich Plasma Injection With a Single Corticosteroid Injection. Am J Sports Med. 2018 Mar;46(4):933-939. . Epub 2018 Jan 2.
  36. Gobbi A, Lad D, Karnatzikos G. The effects of repeated intra-articular PRP injections on clinical outcomes of early osteoarthritis of the knee. Knee Surg Sports Traumatol Arthrosc. 2014 Apr 20.

For more references see also

For references re combination injection therapy see here

For references re rotator cuff and shoulder PRP see here