Dr Iain Duncan

Relative efficacy and safety of topical non-steroidal anti-inflammatory drugs for osteoarthritis: a systematic review and network meta-analysis of randomised controlled trials and observational studies

Chao Zeng, Jie Wei2, Monica S M Persson et al.View post Objectives To compare the efficacy and safety of topical non-steroidal anti-inflammatory drugs (NSAIDs), including salicylate, for the treatment of osteoarthritis (OA). Methods PubMed, Embase, Cochrane Library and Web of Science were searched from 1966 to January 2017. Randomised controlled trials (RCTs) comparing topical NSAIDs […]

PRP (Platelet rich plasma) for Osteoarthritis of the Knee

Iain Duncan February 2018 We have now successfully undertaken a series of platelet rich plasma (PRP) injections in OA knee and most have had more advanced disease than is ideal (the best responders have the least radiological changes), but ~80% have had longer and better responses to PRP than earlier intra-articulator corticosteroid treatments. This is […]

lateral epicondylitis

Lateral Epicondylitis: A Therapy Update

Background  Definition: Lateral epicondylitis is a common, painful condition characterized by pain at the lateral side of the elbow, that increases during gripping or squeezing. Though sometimes referred to as “tennis elbow” it occurs mostly in middle aged adults regardless of sporting activity.  Light microscopy reveals both an excess of fibroblasts and blood vessels that […]

PRP (platelet rich plasma) injections for osteoarthritis

Iain Duncan February 2016 I understand the rationale and use of platelet rich plasma (PRP) for tendon problems but I am continually asked about PRP injections for osteoarthritis.  It is less intuitive than its use for tendon pathologies, where the PRP can be seen to simulate a normal healing response. PRP is not “normal” in joints […]

Injection therapies for plantar fasciopathy (‘plantar fasciitis’): a systematic review and network meta-analysis of 22 randomised controlled trials

Konstantinos Tsikopoulos, Haris S Vasiliadis and Dimitris Mavridis. Abstract Objective To compare the efficacy of different injection therapies for plantar fasciopathy (historically known as ‘plantar fasciitis’). Design Systematic review and network meta-analysis. Data sources Electronic databases (MEDLINE, CENTRAL, Web of Science and Scopus) were searched up to 11 July 2015 for completed studies. Eligibility criteria for selecting […]

Caution about Steroid Injections before total hip replacement

This abstract reproduced courtesy of The Journal of Arthroplasty. The Timing of Total Hip Arthroplasty After Intraarticular Hip Injection Affects Postoperative Infection Risk Brian C. Werner, MD, Jourdan M. Cancienne, MD, James A. Browne, MD Department of Orthopaedic Surgery, University of Virginia Health System, Box 800159, Charlottesville, Virginia   DOI: http://dx.doi.org/10.1016/j.arth.2015.08.032 Background The data regarding any association […]